Gene name:
IMPA2 (IMP.18P) ;
Protein name:
Inositol monophosphatase 2 (IMP 2;IMPase 2) ;
Alternative:
Myo-inositol monophosphatase A2 ;Inositol-1(or 4)-monophosphatase 2 ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
Can use myo-inositol monophosphates, scylloinositol 1,4-diphosphate, glucose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates. Has been implicated as the pharmacological target for lithium Li(+) action in brain.
Subcellular Location:
N/A
Protein Attributes:
50:
MKPSGEDQAA | LAAGPWEECF | QAAVQLALRA | GQIIRKALTE | EKRVSTKTSA |
100:
ADLVTETDHL | VEDLIISELR | ERFPSHRFIA | EEAAASGAKC | VLTHSPTWII |
150:
DPIDGTCNFV | HRFPTVAVSI | GFAVRQELEF | GVIYHCTEER | LYTGRRGRGA |
200:
FCNGQRLRVS | GETDLSKALV | LTEIGPKRDP | ATLKLFLSNM | ERLLHAKAHG |
250:
VRVIGSSTLA | LCHLASGAAD | AYYQFGLHCW | DLAAATVIIR | EAGGIVIDTS |
288:
GGPLDLMACR | VVAASTREMA | MLIAQALQTI | NYGRDDEK
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Mouse
ELISA Kit for Human IMP 2
ELISA Kit for Human IMP 2
ELISA Kit for Human IMP 2
Polyclonal Antibody for Human IMP 2
Polyclonal Antibody for Human IMP 2
Polyclonal Antibody for Human IMP 2
Monoclonal Antibody for Human IMP 2
Monoclonal Antibody for Human IMP 2
Monoclonal Antibody for Human IMP 2
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA]
3.
"Molecular characterization of a novel form of human brain inositol monophosphatase A2b."
Parthasarathy L.
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Parthasarathy R.
Submitted (1999-10) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
4.
"Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
Kalnine N.
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Chen X.
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Rolfs A.
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Halleck A.
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Eisenstein S.
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Koundinya M.
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Farmer A.
Submitted (2003-05) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA]
6.
Mural R.J.
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Istrail S.
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Sutton G.G.
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Florea L.
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Halpern A.L.
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Mobarry C.M.
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Myers E.W.
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Venter J.C.
more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue :
Skin .
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : ENZYME REGULATION
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;MUTAGENESIS OF ASP-104;ENZYME REGULATION;COFACTOR;BIOPHYSICOCHEMICAL PROPERTIES;HOMODIMERIZATION
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
11.
"Crystal structure of human myo-inositol monophosphatase 2, the product of the putative susceptibility gene for bipolar disorder, schizophrenia, and febrile seizures."
Arai R.
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Ito K.
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Ohnishi T.
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Ohba H.
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Akasaka R.
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Bessho Y.
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Hanawa-Suetsugu K.
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Yoshikawa T.
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Shirouzu M.
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Yokoyama S.
Proteins67:732-742(2007)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (2.7 ANGSTROMS) IN COMPLEX WITH SUBSTRATE;HOMODIMERIZATION
12.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (2.4 ANGSTROMS) OF 16-288